Posts tagged with ‘heart’
It turns out that clogged interstates may contribute to clogged arteries. ucirvine graduate researcher Sharine Wittkopp looks at how the increased air pollution caused by vehicle congestion causes blood pressure to rise and arteries to inflame, increasing incidents of heart attack and stroke.
Wittkoop’s data can provide policymakers and the public with a fuller picture of the impact of emissions.
I hope that an awareness of this problem will help strengthen policies designed to decrease emissions and reduce exposure-associated heart disease risk.
Keep up the great work, Sharine! As UC President Janet Napolitano recently said, “graduate students and post-docs are the essential links between teaching for California and researching for the world.”
* Great illustration created by ucresearch producer, Jess Wheelock
A blood test that’s commonly used to determine whether heart transplant recipients are rejecting their new organ can also serve as a ‘crystal ball’ to predict potential rejection-related problems months into the future. Dr. Mario Deng, study leader and head of UCLA’s integrated heart transplant program, says the AlloMap blood test measures changes in the expression of about a dozen genes over a period of time.
Patients who were clinically stable, who had more than one AlloMap blood test in the same range were seemingly doing really well. In contrast, patients who were not clinically stable and who had an AlloMap blood test that was variable over time had a much more clinically bumpy course.
Before, heart transplant recipients underwent routing monitoring by undergoing an invasive, heart-muscle biopsy. Now, the AlloMap test offers these patients a non-invasive, personalized medicine approach.
We can now systematically tailor the immune-suppression dose to the individual person’s needs and that was not possible before.